Greater Philadelphia presents to innovators and entrepreneurs alike one of the world’s most robust health care infrastructures—a knowledge economy supported by a vibrant ecosystem of top-rated academic and research institutions and a renowned health care delivery system.

We are a region working together more than ever before through every facet of the health care continuum to leverage the assets, resources and willpower required to expedite market breakthroughs. Joining the nine founding members of the Health Care Innovation Collaborative are our partner organizations whose resources are available to Open Call applicants.

Advanced Manufacturing for the Medical Device Industry

An initiative of Ben Franklin Technology Partners of Southeastern Pennsylvania, with funding from the U.S. Economic Development Administration, AMMDI assists entrepreneurs to accelerate the development, commercialization and manufacture of the next generation of medical devices employing new materials, software and advanced manufacturing processes in the Greater Philadelphia region

Alliance of Women Entrepreneurs

Founded in 1996, the Alliance of Women Entrepreneurs is the Mid-Atlantic region’s largest organization dedicated to fostering high-growth businesses founded or led by women. Through its educational and networking events, AWE fosters relationships within the entrepreneurial community to identify, cultivate, and inspire women entrepreneurs. AWE is proud of their members, many of whom have founded and led innovative ventures that have resulted in significant return on capital for investors.

Ben Franklin Technology Partners

combines the best practices of early stage investing with a higher purpose: to lead the region’s technology community to new heights, creating jobs and transforming lives.

For over 30 years, Ben has been the leading seed stage capital provider for the region’s technology sectors, investing over $175 million in more than 1,750 regional technology companies, many of which have gone on to become industry leaders. Ben Franklin has also launched university/industry partnerships that accelerate scientific discoveries to commercialization, and has seeded regional initiatives that strengthen our entrepreneurial community.

Ben Franklin Technology Partners is an initiative of the Pennsylvania Department of Community and Economic Development. In addition to its numerous investment partners, Ben Franklin receives funding from the Ben Franklin Technology Development Authority.


provides early-stage capital for companies located in the mid-Atlantic region that are developing technologies to improve human health. They invest exclusively in opportunities that have the potential to improve human health with an emphasis on therapeutic agents, including platform technologies, research tools, medical devices, diagnostics and healthcare IT.

Entrepreneur Works

is a non-profit 501(c)(3) corporation that provides supportive services to entrepreneurs and small business owners to assist them in starting or incorporating an existing business better.

With office locations in Philadelphia and Chester, PA, Entrepreneur Works provides a comprehensive array of financial and business development services including: small business and peer loans, business skills workshops and classes, business consulting, and networking.

Greater Philadelphia Alliance for Capital and Technologies

vision is to be a premier resource for emerging growth companies in Technology and Healthcare industries. PACT’s mission is to create a strategic hub for the region’s emerging growth companies while bringing a competitive edge to the Greater Philadelphia region.

HealthShare Exchange of Southeastern Pennsylvania, Inc.

Resulting from a number of health care market drivers and challenges, HealthShare Exchange was formed as a collaboration among major healthcare stakeholders, including health plans and the acute care hospitals across the five-county region of Bucks, Chester, Delaware, Montgomery, and Philadelphia counties to enable the electronic exchange of patient information to improve patient outcomes and to manage and lower healthcare costs in the Southeastern Pennsylvania region.

Pennsylvania Bio

mission is to ensure Pennsylvania is the United States hub for the life sciences by creating a business and public policy environment which fosters life sciences growth and success. Pennsylvania is considered the most attractive location in the United States for establishing a life sciences organization by life sciences leaders within the U.S. and by those outside the U.S. seeking to establish U.S. operations.

Pennsylvania Bio was founded 25 years ago by a group of biotech CEOs. Today it’s grown to represent the entire life sciences industry: medical device companies, pharmaceutical companies, investment organizations, academic institutions, and myriad service industries that support the life sciences in Pennsylvania.

Pennsylvania eHealth Partnership Authority.

The purpose of the Pennsylvania eHealth Partnership Authority, which was created through the Pennsylvania eHealth Information Technology Act, is to improve healthcare delivery and healthcare outcomes in Pennsylvania by enabling the secure exchange of health information.

Philadelphia Health IT Circle

is a networking, education, and advocacy group for the Philly digital health scene. Their members include entrepreneurs, investors, healthcare providers, payers, patient-advocacy concerns, and academics who span the spectrum of developers and consumers of digital health products and services.

PHITC bring together a diverse group of stakeholders for quarterly gatherings around hot topics in health care and how technology can be best utilized to overcome barriers to innovation.

Through these meetings, PHITC provides a neutral venue for decision-makers to meet up and discuss new partnerships and ideas. By providing connections between providers, VCs, payers, industry, and Philly’s robust start-up community, PHITC is a driving force for developing a fertile environment for digital health innovation in the Philadelphia region.

Philadelphia Industrial Development Corporation

is a non-profit partnership between the City of Philadelphia and the Greater Philadelphia Chamber of Commerce, founded in 1958. Their mission is to spur investment, support business growth, and foster development that creates jobs, revitalizes neighborhoods, and drives growth to every corner of Philadelphia. To achieve their mission, they attract, manage, and invest public and private resources in the clients, communities, and markets that energize Philadelphia’s economy.

PIDC offer flexible financing tools, a targeted portfolio of industrial and commercial real estate, and decades of Philadelphia-based knowledge to help their clients invest, develop, and grow. They also structure and invest in public-private partnerships for key City policy areas and development priorities.

Philly Startup Leaders

is a community of startup entrepreneurs dedicated to helping each other on their entrepreneurial journeys. They provide the kind of emotional and practical support that can only come from a fellow entrepreneur. Emotionally, they share wisdom, inspiration, and friendship. Practically, they share advice, connections, and resources. They mentor each other and coach new entrepreneurs who are making the transition.

They often collaborate and connect with the larger ecosystem—with people and organizations who are not themselves entrepreneurial. But what makes them so different and so effective is their focus on connecting entrepreneurs with each other. They thrive because we understand that, above all else, startup entrepreneurs need each other.


For Philadelphia’s early stage health care companies, PLEXUS provides a community of passionate entrepreneurs who are leveraging instant and unparalleled access to an extensive network of resources. These include industry experts, senior executives, investors, clinicians, and service providers along with a superbly equipped fabrication facility.

Select Greater Philadelphia (of the Greater Philadelphia Chamber of Commerce)

is a business attraction marketing organization dedicated to promoting the Greater Philadelphia region nationally and globally in order to establish Greater Philadelphia as a top-tier place to do business.

Select assists companies interested in the region by providing detailed information about the 11-county area and gateway services that connect companies with the legal, political, and financial assistance they may need in relocating or expanding in the Greater Philadelphia region.

Through global marketing efforts, Select works to promote the region’s key assets to help build the area’s economy. The Greater Philadelphia region encompasses northern Delaware, southern New Jersey and southeastern Pennsylvania. Select is a private, non-profit organization and is the Business Attraction Marketing unit of the Greater Philadelphia Chamber of Commerce.

The Entrepreneurs’ Forum of Greater Philadelphia

supports the creation and development of high growth firms by delivering essential resources, education and networking opportunities to help entrepreneurs achieve their dreams.

The Forum serves as a clearing house and focal point, offering entrepreneurs, inventors, investors and professional advisors a forum to exchange ideas, advice and investment opportunities. They do this by providing information, programming, resources and networking opportunities to the entrepreneurial community.

The Greater Philadelphia Chamber of Commerce

is the premier advocate of the region’s business community, representing members in 11 counties across three states with one voice. The GPCC is dedicated to promoting regional economic growth, advancing business-friendly public policies, and servicing our members through outstanding programs, benefits and services.

As an advocate for regional development, the Greater Philadelphia Chamber of Commerce is dedicated to supporting and encouraging the continued growth of each of our approximately 4,000 member companies together with the regional business community. The Chamber strives to influence business-friendly legislation in all levels of government, participate in initiatives to improve education and the community, present professional enrichment programs, and provide our members with cost-efficient ways to run their businesses.

TranCelerate BioPharma

A nonprofit collaboration of 16 of the world’s largest pharma and biotech companies, King of Prussia-based TranCelerate BioPharma is working to create global standards for clinical trials data interchange, as well as for patient data privacy.

University City Science Center

Founded in 1963, the Science Center is the oldest and largest urban research park in the United States. They’re a dynamic hub for innovation, entrepreneurship and technology development in the Greater Philadelphia region. The Science Center’s 31 nonprofit shareholders include many of the distinguished colleges, universities, hospitals, and research institutions located throughout Pennsylvania, New Jersey, and Delaware.

The Science Center provides lab and office space for start-up, growing and established companies. They offer business incubation, support services and programming for entrepreneurs and start-up companies. They help move technology out of the lab and into the marketplace, where it can benefit the region and the world.

University Science Center Digital Health Accelerator.

Through its Digital Health Accelerator, the University Science Center offers companies up to $50,000 in funding, office space at the Science Center, professional mentorship, and warm introductions into a variety of healthcare stakeholders, including insurers, pharmaceutical companies, and hospital and research institutions located in and around Philadelphia.

Urban League of Philadelphia

Since 1917, the Urban League of Philadelphia has been empowering the African American community. They are an affiliate of the National Urban League the nation’s oldest and largest community-based movement devoted to empowering African Americans to enter the economic and social mainstream. Their Connect 360 Strategic Plan clearly defines our function as a bridge connecting individuals, civic organizations, corporations, and public officials in the Greater Philadelphia region.